By Michael J. Gonzalez,Jorge R. Miranda-Massari
By Amit Gefen,Daphne Weihs
By Gregory Grant
By Taishin Nomura,Yoshiyuki Asai
By Jose Russo,Irma H. Russo
By Ya-Xiong Tao
Obesity is an outbreak with huge, immense overall healthiness, financial and social burdens. present medicines for weight problems remedy are faraway from perfect when it comes to efficacy and unwanted effects. studies during this quantity of growth in Molecular Biology and Translational technology summarize present prestige in reviews of a couple of G protein-coupled receptors that have been proven to be promising ambitions for weight problems remedies. a few of these receptors additionally reason monogenic weight problems in people.
- Subject subject: weight problems is a deadly disease and G protein-coupled receptors are promising drug goals, with major strength as new anti-obesity drugs
- Chapters are written through top experts
By Dragan Primorac,Moses Schanfield
Forensic DNA functions: An Interdisciplinary Perspective was once built as an outgrowth of a convention held by means of the overseas Society of utilized organic Sciences. the subject used to be human genome–based functions in forensic technological know-how, anthropology, and individualized drugs. Assembling the contributions of members from various areas world wide, this quantity is designed as either a textbook for forensic molecular biology scholars and a reference for practitioners and people within the criminal system.
The e-book starts off with the background and improvement of DNA typing and profiling for felony and civil reasons. It discusses the statistical interpretation of effects with case examples, mitochondrial DNA trying out, Y unmarried nucleotide polymorphisms (SNPs) and brief tandem repeats (STRs), and X SNP and STR checking out. It additionally explores low reproduction quantity DNA typing, combinations, and caliber insurance and keep watch over.
The moment part examines the gathering and maintenance of organic facts lower than a number of assorted situations and the identity of human remains—including in mass catastrophe settings. It discusses purposes to bioterrorism investigations, animal DNA trying out in legal circumstances, pedigree questions and natural world forensic difficulties, functions in forensic entomology, and forensic botany.
The 3rd part explores contemporary advancements and new applied sciences, together with the rigorous id of tissue of beginning, mtDNA profiling utilizing immobilized probe strips, chips and next-generation sequencing, using SNPs to examine phenotypic features, and the "molecular post-mortem" that appears at features of toxicogenetics and pharmacogenetics.
The ebook concludes with a dialogue on legislations, ethics, and coverage. It examines using DNA proof within the felony justice method in either the us and Europe, moral issues
in forensic laboratory practices, familial searches, DNA databases, ancestry searches, actual phenotyping, and file writing. The members additionally learn DNA functions in immigration and human trafficking instances and overseas views on DNA databases.
By Domnita Crisan (Ed.),Domnita Crisan
Hematopathology: Genomic Mechanisms of Neoplastic illnesses will preserve physicians abreast of the swift and intricate adjustments in genomic drugs, as exemplified through the molecular pathology of hematologic malignancies. This well timed quantity will replace physicians at the complexities of genomic lesions, in addition to provide an built-in framework encompassing molecular prognosis, the recent WHO type of hematologic neoplasms with specialize in molecular pathology, prognostic worth of molecular exams, and molecular tracking of reaction to gene-targeted treatment. As such, it is going to be of serious price to hematologists, oncologists, pathologists, inner medication and pediatric experts, in addition to bioscientific employees and laboratorians in inner most hospitals and educational associations.
By Lynn Loriaux
Endocrine Emergencies: reputation and remedy offers a cutting-edge replace at the administration of endocrine, diabetic, and metabolic emergencies. built via well known specialists, this accomplished and straightforward to learn identify brings the sphere totally brand new, atmosphere a excessive normal for analysis and remedy in every one category. All chapters start with a precis that offers, in centred shape, what the general practitioner must recognize to start the evaluate and emergency therapy of the identified endocrine emergencies. this is often through a longer dialogue of the pathophysiology that may be learn after preliminary therapy has started. protecting such parts as hypoglycemia, acute adrenal insufficiency, ovarian hyperstimulation syndrome, thyroid typhoon, and pituitary apoplexy, simply to identify numerous, Endocrine Emergencies: attractiveness and therapy is an invaluable, sensible source that would be of great curiosity to endocrinologists, inner medication and emergency room physicians, fellows and residents.
By Mahendra S. Rao,Mohan C. Vemuri,Melissa Carpenter